ADAMANTINOMA TREATMENT

Adamantinoma is a rare low-grade malignant bone tumor of uncertain histogenesis, which occurs commonly in the diaphyses and metaphyses of the tibia.

It shows biphasic patterns of epithelial cells and osteofibrous components. There are two types of adamantinoma the classical and the differentiated type, which resembles osteofibrous dysplasia.

Adamantinoma is a rare tumor accounting for approximately 0.4% of all primary malignant bone tumors. There is a slight male predominance with a sex ratio of 5:4.

The most common sites involved by adamantinoma are the anterior metaphysis or diaphysis of the tibia. Other sites include the fibula, ulna, femur, humerus, and radius.

GENETICS: extra copies of chromosomes 7, 8, 12, 19, and 21 have been detected in classic as well as osteofibrous dysplasia-like forms of adamantinoma.

IT IS DIAGNOSED WITH THE HELP OF: radiograph -  x-ray, the tumor is typically well-circumscribed, cortical, multilobulated, and osteolytic. Intralesional opacities, septation, and peripheral sclerosis may also be seen. multifocal radiolucencies, which are surrounded by ring-shaped densities, produce the characteristic ''soap-bubble'' appearance. CT scan plays a role in the routine work-up of adamantinomas. MRI plays a crucial role in locoregional staging since it depicts distant cortical foci, intramedullary and soft tissue extension. Most effective treatment of adamantinoma is wide excision with clear margins.