This is a group of disorders characterized by extracellular deposits of a protein in abnormal fibrillar form, resistant to degradation. The following are the systemic forms of amyloidosis.
Amyloid deposition is also a feature of Alzheimer's disease, type 2 diabetes mellitus and haemodialysis related amyloidosis.
PRIMARY AMYLOIDOSIS: - Proliferation of plasma cell clone, amyloidogenic monoclonal Immunoglobulins , Fibrillar light chain protein deposition, Organ failure.
DEATH: - Associations: Myeloma, Waldenstroms, lymphoma
ORGANS INVOLVED: - kidneys, heart, nerves, gut, vascular system.
SECONDARY AMYLOIDOSIS: - Here amyloid is derived from serum amyloid A,an acute phase protein, reflecting chronic inflammation in rheumatoid arthritis,familial Mediterranean fever and chronic infections like TB, bronchiectasis, osteomyelitis.
FAMILIAL AMYLOIDOSIS: - Usually causes a sensory or autonomic Neuropathy.
CONCLUSION: -
The disease condition and it's symptoms are managed by the help of many effective homoeopathic medicines. The further progress of the Amorphous fibrillar protein in a diseased state can be prevented by homoeopathic mode of treatment.