Macrocytosis is common, often due to alcohol excess without any accompanying anaemia. Although only 5% are due to B12 Deficiency, pernicious anaemia is the most common cause of a macrocytic anaemia in western countries.
B12 and folate deficiencies are megaloblastic anaemias. A megaloblast is a cell in which nuclear maturation is delayed compared with the cytoplasm. This occurs with B12 and folate deficiencies,as they are both required for DNA synthesis.
CAUSES OF MACROCYTOSIS: -
B12 Deficiency, folate deficiencies, cytotoxic drugs, alcohol, reticulocytosis, liver disease, hypothyroidism, pregnancy, Myelodysplasia, aplastic anaemia etc.
TESTS: - B12 and folate Deficiency result in similar blood film and bone marrow biopsy appearances.
BLOOD FILM: Hyper segmented polymorphs in B12 and folate Deficiency.
OTHER TESTS: LFT, TFT, serum B12 and serum folate.
Bone marrow biopsy is indicated if the cause is not revealed by the above tests.
CONCLUSION: -
There are many Homoeopathic remedies which can very efficiently manage the disease condition, it's complications, it's symptoms and can help in preventing further progress of the disease.
ABHI HOMEO HALL is a one and half decade old renowned clinic that offers the best quality, non-toxic and highly effective treatment in Ranchi, Patna and Delhi.
Read More
