MENETRIER’S DISEASE AND EFFECTIVENESS OF HOMOEOPATHIC MEDICINES FOR MANAGING IT

Menetrier's disease is a rare disorder characterized by giant mucosal folds in the proximal part of the stomach, diminished acid secretion, and a protein loosing state with hypoalbuminaemia. Other names are hypoproteinemic hypertrophic gastropathy and giant hypertrophic gastritis.

In this rare condition, the gastric pits are elongated and tortuous, with replacement of the parietal and chief cells by mucus-secreting cells. - The cause is unknown but there is excessive production of TGF-α. As a result, the mucosal folds of the body and fundus are greatly enlarged. -Most patients are hypochlorhydric. Whilst some patients have upper gastrointestinal symptoms, the majority present in middle or old age with protein losing enteropathy due to exudation from the gastric mucosa. -Endoscopy shows enlarged, nodular and coarse folds, although biopsies may not be deep enough to show all the histological features. Treatment with ant secretory drugs, may be a bit helpful.

SYMPTOMS: -

• Stomach pain,
• Diarrhoea,
• Burning,aching and discomfort in upper abdomen.
• Acid reflux and heartburn.
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• Nausea and vomiting.
• Bleeding from digestive tract.
• Weight loss.

CONCLUSION: -

There are many Homoeopathic remedies which can help in managing the problems associated with Zollinger Ellison Syndrome. One should always consult with their nearest Homoeopathic physician to get the medicines prescribed.