Oral Lichen Planus is a chronic inflammatory, a non-infectious disease that causes lesions on the buccal mucosa, tongue and/or gums. It affects approximately 1-2% of the general adult population. Although oral Lichen Planus predominantly occurs in adults older than 40 years, younger adults and children can also be affected. Lichen Planus may affect either skin or mouth or genitals or the nails; or in any combination of two or more.
The role of autoimmunity in the pathogenesis of oral Lichen Planus is supported by many studies. It may be induced by certain drugs (mentioned below), contact allergens in dental materials or toothpaste, mechanical trauma, viral infection or some unidentified agents.
Oral Lichen Planus may be caused by more than one cause. Some drugs often induce it. Stress is also a major trigger factor. The genetic factor is usually found in the background. Oral Lichen Planus is considered pre-cancerous.