– Classic FUO: Etiologies to consider include:
– Nosocomial FUO: More than 50% of cases are due to infection (e.g., infected foreign bodies or catheters, Clostridium difficile colitis, sinusitis). Noninfectious causes (e.g., drug fever, pulmonary embolism, acalculous cholecystitis) account for ~25% of cases.
– Neutropenic FUO: More than 50–60% of pts with febrile neutropenia are infected, and 20% are bacteremic. Candida and Aspergillus infections are common.
– HIV-associated FUO: More than 80% of pts are infected, with the specific infectious etiology dependent on the extent of immunosuppression and the geographic region. Drug fever and lymphoma are also possible etiologies.
The medicines that can be thought of use are:-