ADDISON’S DISEASE

It is an autoimmune disease. Where the adrenal is being attacked by the immune cell, causing insufficiency in production of cortisol and aldosterone hormone.

ETIOLOGY

Primary adrenocortical insufficiency ( Cortisol and aldosterone deficiency) is most commonly due to autoimmune destruction of the adrenal cortex.

Secondary adrenal insufficiency (not considered Addison’s disease) is due to inadequate ACTH stimulation of the adrenal cortex due to hypopituitarism or suppression of pituitary ACTH by excess steroid admistration.

Same symptoms as in Addison’s disease except no pigmentation changes and no  hhyperkalemia.

SIGN AND SYMPTOMS OF ADDISON’S DISEASE

1. Weakness and fatigue.
2. Weight loss.
3. Abdominal pain, anorexia, nausea, vomiting.
4. Hyper pigmentation of skin and mucous membranes.
5. Hypotension and orthostatic hypotension.
6.  
7. Electrolyte imbalance.
8. ADRENAL CRISIS: It is life threatening situation, where there is low blood pressure, low level of blood sugar and high blood level of potassium. Need a immediate medical care.

DIAGNOSIS OF ADDISON’S DISEASE

USG AND CT Scan: for visualizing the gland enlargement, calcification, solid or hemorrhage.

Rapid adenocorticotropic hormone (ACTH) this test confirms the adrenal hypo-function. 

HOMOEOPATHIC APPROACH FOR ADDISON’S DISEASE

• Carcinosinum
• Gelsemium
• Kalium Phosphoricum
• Thyroidinum
• Pituitary