FEVER OF UNKNOWN ORIGIN

• Etiology: The likely etiologies differ with the category of FUO.

 – Classic FUO: Etiologies to consider include:

• Infection—e.g., extrapulmonary tuberculosis; EBV, CMV, or HIV infection; occult abscesses; endocarditis; fungal disease. Infections remain a leading diagnosable cause of FUO, accounting for ~25% of cases in recent studies.
• Neoplasm—e.g., colon cancer
• Miscellaneous noninfectious inflammatory diseases—e.g., systemic rheumatologic disease, vasculitis, granulomatous disease. In pts >50 years old, giant-cell arteritis accounts for 15–20% of FUO cases.
• Miscellaneous diseases—e.g., pulmonary embolism, hereditary fever syndromes, drug fever, factitious fevers

 – Nosocomial FUO: More than 50% of cases are due to infection (e.g., infected foreign bodies or catheters, Clostridium difficile colitis, sinusitis). Noninfectious causes (e.g., drug fever, pulmonary embolism, acalculous cholecystitis) account for ~25% of cases.

 – Neutropenic FUO: More than 50–60% of pts with febrile neutropenia are infected, and 20% are bacteremic. Candida and Aspergillus infections are common.

 – HIV-associated FUO: More than 80% of pts are infected, with the specific infectious etiology dependent on the extent of immunosuppression and the geographic region. Drug fever and lymphoma are also possible etiologies.

HOMEOPATHIC MEDICINES: -

The medicines that can be thought of use are:-

• Arnica
• Bryonia
• Belladonna
• Gelsemium
• Hepar Sulphur
• Glonoine