LAURENCE–MOON SYNDROME

Laurence–Moon syndrome (LMS) is a rare autosomal recessive genetic disorder associated with retinitis pigmentosa, spastic paraplegia, and mental disabilities.

SIGNS AND SYMPTOMS

Intellectual disability, hexadactyly, central diabetes insipidus, blindness (usually by 30 years due to central retinal degeneration).

DIAGNOSIS

The syndrome was originally thought to have five cardinal features (and recently a sixth was added), on the basis of which a diagnostic criterion was developed: 4 primary features or 3 primary features and 2 secondary features must be present.

THE PRIMARY FEATURES ARE:

1. Polydactyly
2. Rod-cone dystrophy
3. Learning disabilities
4. Obesity
5. Hypogonadism in males
6. Renal abnormalities

WHILE THE SECONDARY FEATURES ARE STATED TO BE AS:

1. Speech disorder and/or developmental delay
2. Ophthalmic abnormalities other than rod-cone dystrophy (strabismus, cataract, astigmatism etc.)
3. Brachydactyly or Syndactyly
4. Polyuria and/or polydipsia (nephrogenic diabetes insipidus)
5. Ataxia, poor coordination, imbalance
6. Mild spasticity (especially lower limbs)
7. Diabetes mellitus
8. Dental crowding, hypodontia, small roots, high arched palate
9. Congenital heart disease
10. Hepatic fibrosis

HOMOEOPATHIC APPROACH

Homoeopathy today is a rapidly growing system and is being practiced all over the world. It strength lies in its evident effectiveness as it takes a holistic approach towards the sick individual through promotion of inner balance at mental, emotional, spiritual and physical levels. When  is concerned there are many effective medicines available in Homoeopathy , but the selection depends upon the individuality of the patient , considering mental and physical symptoms

Few homoeopathic medicine can be thought of in the treatment of Laurence–Moon syndrome are:

iodum, thyroidinum, natrum mur, bromium, etc.